Cheng Ji

PIBBS & RSP Mentor; Professor
Research Medicine, Biochemical & Molecular Biology
Keck School of Medicine of USC

Research Topics

  • Organelle (ER/Golgi/lysosome) Stress and Liver Diseases;
  • Hepatotoxicity of Alcohol and Antiviral Drugs;
  • Tackling Alcohol Intoxication with Nanotechnology

Research Images

Research Overview

(see all in PubMed or Google Scholar)
(1) Effect of artesunate supplementation on bacterial translocation and dysbiosis of gut microbiota in rats with liver cirrhosis. World J Gastroenterol. 2016; 22(10):2949; PMID: 26973391.
(2) Advance & New Concept in Alcohol-Induced Organelle Stress, UPR and Organ Damage. Biomolecules 2015; 5(2):1099. PMID: 26047032.
(3) Effects of Alcohol and Anti-HIV Drugs on Cellular Stress Responses in Primary Liver Cells. Alcohol Clin Exp Res. 2015; 39(1):11.
(4) Enhanced expression of GRP78 correlates with malondialdehyde levels… Exp Ther Med. 2015;10(6):2119. PMID: 26668603.
(5) Overexpression of GRP78 promotes cardiomyocyte apoptosis in a rat model of liver cirrhosis. Int J Clin Exp Pathol 2015; 8(8): 9256; PMID:26464674.
(6) New Insights into the Pathogenesis of Alcohol-Induced ER Stress and Liver Diseases. Int. J. of Hepatology, vol. 2014; 513787; PMID: 2486870
(7) Critical Role of GRP78 in Pulmonary Microvascular Remodeling. Gene. 2014; 545(1):156; PMID: 24768185
(8) Expression of GRP78 in hepatopulmonary syndrome. Gene. 2014; 537:115-119; PMID: 24334118
(9) Altered Methylation of ERAD in Alcohol-induced Liver Tumors. Frontiers in Genetics 2013; 4: 224; PMCID: PMC3813967
(10) Enzyme Nanocomplexes as Antidotes for Alcohol Intoxication. Nature Nanotech. 2013; 8:187
(11) ER stress, Cyclin D, ERα variants, and Liver Tumorigenesis. J Gastro. Hepatol. 2013; 28(3):576
(12) Tregs, MMP9/13, TGF-β and acute liver injury. J Mol Cell Biol. 2013; 5(6):369. PMID: 24280647