Houda Alachkar

PIBBS Mentor

Assistant Professor
Clinical Pharmacy
USC School of Pharmacy

Research Topics

  • Experimental Cancer Therapeutics
  • Pharmacogenomics
  • Immunopharmacogenomics
  • Acute Myeloid Leukemia

Research Overview

The revolution in sequencing technologies has given the momentum for the emerging genomics and personalized medicine era that led to great discoveries particularly in cancer research. Translating these discoveries into the clinic however has moved at a much slower pace. It is evident that pharmacogenomic variation in both somatic mutations in cancer cells and germline variants in normal cells hosting the cancer influence the disease outcome and response to treatment.

The Alachkar lab is focused on applying genomic information in the identification and functional characterization of cancer targets, and in the preclinical and clinical developments of potential targeted therapeutic approaches with particular interest in acute myeloid leukemia.