PIBBS Alumni

Name Mentor/ PI Year Dissertation
Alan Okada Robert Chow 2016 Enhancing and Inhibiting Diabetic Amyloid Misfolding
Jonathan Tucci Steven Mittleman 2016 The Role of Adipocyte-Derived Free-Fatty Acids in Acute Lymphoblastic Leukemia
Priyamvada Jayaprakash

 

Wei Li 2016 Mechanism of secretion and function of heat shock protein-90 (Hsp90) family genes
Chia-Lin Chen Keigo Machida 2016 Targeting tumor-initiating stem-like cells through metabolic and epigenetic regulations
Sara Pirooz Chengyu Liang 2016 Virus Customization of Host Protein Machinery for Efficient Propagation
Jieli Shen Amy Lee 2016 The role of glucose-regulated proteins in endometrial and pancreatic cancers
Astgik Petrosyan Laura Perin 2016 Renal Extracellular Matrix Bioactivity in a Range of Physiological States: Novel Insights for Kidney Regeneration
Ingrid Lua Kinji Asahina 2016 DETERMINATION OF THE SOURCE OF MYOFIBROBLASTS AND THERAPEUTIC STRATEGY AGAINST FIBROSIS
Justin Schaal Michael Selsted 2016 “Immunomodulatory Properties, Mechanisms, and Therapeutic Potential of Macrocyclic Theta Defensins”
In Young Choi Valter Longo 2016 The Effects of Prolonged Fasting/ Fasting Mimicking Diet (FMD) on CNS Protection, Regeneration, and Treatment
Ayesha Bhatia Wei Li 2016 The Role of Secreted Hsp90α in Tissue Repair and Cancer
Jun Zhao Pinghui Feng 2016 Study of protein deamidation in innate immune signaling
Yang Liu Tim Triche 2016 Functional role of a Ewing-sarcoma-specific vlncRNA in tumor growth and progression
Yuki Yamaguchi Henry Sucov 2016 Developmental Biology of Epicardial Adipose Tissue
Malini Iyer Richard Watanabe 2016 Role Of Sympathetic Nervous System In Metabolic Function
Christopher Duymich Peter Jones 2016 EFFECTS OF CHROMATIN REGULATORS DURING CARCINOGENESIS
Aditi Bauskar M. Elizabeth Fini 2016 New roles for the glycoprotein Clusterin at the ocular surface
Cynthia Neben Amy Merrill 2016 Fgfr2 regulates ribosome biogenesis during osteoprogenitor cell differentiation
Yu Gyoung Tak Peggy Farnham 2016 Functional Characterization of colon cancer risk-associated enhancers: connecting risk loci to risk genes
Lijing Yao Peggy Farnham 2015 Identification and characterization of cancer-associated enhancers
Kyu Eui Kim Young-Kwon Hong 2015 LYMPHATIC CELL ENVIRONMENT PROMOTES SUSTAINED KSHV LYTIC REPLICATION AND VIRAL MAINTENANCE
Niyati Jhaveri Florence Hofman 2015 Targeting Glioma Cancer Stem Cells for the Treatment of Glioblastoma multiforme
Chen Li Vijay Kalra 2015 The Role of miRNA and its Regulation in Pulmonary Hypertension in Sickle Cell Disease
Sapna Jain Gregor Adams 2015 Role of the Bone Marrow Niche Components in B-cell Malignancies
Xia Sheng Steve Mittleman 2015 The Role of Adipocytes in Acute Lymphoblastic Leukemia Cell Migration and Survival Against Daunorubicin
Keerthi Boddupally Agnieszka Kobielak 2015 Identification and characterization of adult stem cells in the oral cavity
Jessica Rathbun Paula Cannon 2015 DRUG DISCOVERY FOR HIGHLY PATHOGENIC HEMORRHAGIC FEVER VIRUSES
David Gate Terrence Town 2015 Enabling Alzheimer’s Abeta phagocytosis by targeting IRAK-M innate immunity
Christine Marion Louis Dubeau 2015 UNDERSTANDING THE ROLE OF BRCA1 AND AURORA A KINASE IN POLYPLOIDY DEVELOPMENT IN OVARIAN CARCINOMA PRECURSOR CELLS
Mark Ambroso Ralf Langen 2015 THE STRUCTURE AND FUNCTION OF MEMBRANE CURVING PROTEINS ON DIFFERENT MEMBRANE SHAPES AND THEIR REGULATION BY POST-TRANSLATIONAL MODIFICATIONS
Amanda Crow Hooman Allayee 2015 Application of Genetic Association Methods in Mice to Understand Phenotypes with a Complex Etiology
Mario Pulido Ite Larid-Offringa 2015 Characterization of small cell lung cancer-associated anti-ELAVL4 immune response for immunotherapy development using a transgenic mouse model
Michael Krainock Richard Kim 2015 Histone 3 Lysine 4 Tri-Methylation in the Regulation of Epicardial Epithelial-to-Mesenchymal Transformation
Marie Rippen Kris Kobielak 2015 The Function of BS69 in Mouse Embryogenesis and Embryonic Stem Cell Differentiation
Yassan Abdolazimi Neil Segil 2015 The role of HES/HEY transcriptional repressors in specification and maintenance of cell fate in the mouse organ of Corti
Candace Johnson Ite Larid-Offringa 2015 CpG Poor Promoter SULT1C2 Regulated by DNA Methylation and is Induced by Cigarette Smoke Condensate in Lung Cell Lines
Malaina Gaddis Peggy Farnham 2015 Altering the Epigenome and Transcriptome of Colon and Pancreatic Cancer Cells using the Inhibitors ICG-001 and C646
Julie Jang Alan Epstein 2015 Conjugation of CpG Oligodeoxynucleotides to Tumor-Targeting Antibodies for Immunotherapy of Solid Tumors
Emily Chen James Knowles 2015 Genomic variant analysis in whole blood of recurrent early-onset major depression patients and differential expression in BA25 of suicide completers with major depression
Natalie Kegulian Ralf Langen 2015 Before They Were Amyloid: Understanding the Toxicity of Disease-Associated Monomers and Oligomers Prior to Their Aggregation
Janise Deming Cheryl Craft 2015 Cone Arrestin 4 Contributes to Vision, Cone Health, and Desensitization of the Dopamine Receptor D4
Thomas Schmidt Tobias Ulmer 2015  Dual Effects of Transmembrane Proline Residues on Integrin Function
Watanabe Go Michael Lieber 2015 X-RAY STRUCTURAL STUDIES ON DNA-DEPENDENT PROTEIN KINASE CATALYTIC SUBUNIT:DNA CO-CRYSTALS
Brian Wu Edward Schroeder 2015 Investigations into causes of muscle atrophy and improving clinical outcomes following lower limb surgeries
Lauren Gyllenhammer Michael Goran 2015 Quality versus Quantity: How Adipose Tissue Accumulation and Immune Cell Profile Associate with Risk for Type 2 Diabetes in Minority Children and Adults
Sarah Vargas Alan Watts 2015 Deciphering the neural networks responsible for controlling feeding during and after dehydration-anorexia.
Andrew Woodham Martin Kast 2015 HUMAN PAPILLOMAVIRUS TYPE 16 ENTRY VIA THE ANNEXIN A2 HETEROTETRAMER LEADS TO INFECTION AND IMMUNE EVASION
Lisa Yan Martin Kast 2015 LIGHT-ING UP PROSTATE CANCER: REMODELING THE TUMOR MICROENVIRONMENT AND ENHANCING THERAPEUTIC VACCINE EFFICACY THROUGH FORCED LIGHT EXPRESSION IN PROSTATE CANCER
Genyuan Zhu Amy Lee 2015 THE ROLE OF ENDOPLASMIC RETICULUM CHAPERONES IN ADIPOGENESIS, LIVER CANCER AND MAMMARY GLAND DEVELOPMENT
Casey Brewer John Wood 2014 Sex differences and steroid modulation of cardiac iron in a mouse model of iron overload.
Kevin Brulois Jae U. Jung 2014 KSHV-mediated Modulation of Immunoreceptor Surface Expression
Krishnakali Dasgupta Robert Maxson 2014 ELUCIDATING THE ROLE OF NEURAL CREST SPECIFIC STAT3 SIGNALING IN MAINTAINING CORONAL SUTURE PATENCY DURING EMBRYONIC DEVELOPMENT
Jamie Hsiung David Hinton 2014 Characterization of Human Embryonic Stem Cell Derived Retinal Pigment Epithelial Cells for Age-Related Macular Degeneration
Fides Lay Peter Jones 2014 Functional DNA Methylation Changes in Normal and Cancer Cells
Yaping Liu Ben Berman 2014 Understanding DNA methylation and nucleosome organization in cancer cells using single molecule sequencing
In Mah Francesca Mariani 2014 Roles of three domains of CCAR1 in transcription activation by nuclear receptors
Anthony Martin Baruch Frenkel 2014 Runx2 & Sex Steroids: Molecular Mechanisms in Regulating Bone Turnover
Kathryn O’Brien Wei Li 2014 Extracellular Hsp90α in Diabetic Wound Healing: Structure, Function, and Mechanism of Action
Suzi Sanchez Si-Yi Chen 2014 SMYD5 Regulates Activation-Induced Inflammatory Responses and Cytokine Production in Murine Macrophages
Chih-l Tai Qi-long Ying 2014 PLEOTROPIC POTENTIAL OF STAT3 IN DETERMINING SELF-RENEWAL, APOPTOSIS, AND DIFFERENTIATION IN MOUSE EMBRYONIC STEM CELLS
Dai-Ying Wu Michael Stallcup 2014 Using genomics to understand the gene selectivity of steroid hormone receptors
Sicong Li Michael Lieber 2013 Mechanisms of Nucleases in Non-Homologous DNA End Joining
Vijayalakshmi Nandakumar Si Yi Chen 2013 The essential role of histone H2A deubiquitinase mysmi in natural killer cell maturation and HSC homeostasis
Trisha Staab Derek Sieburth 2013 Regulation of neuronal function by the conserved SKN-1/NRF stress response pathway in Caenorhabditis elegans
Han Wang Derek Sieburth 2013 Genetic and Molecular Analysis of a Rhythmic Behavior in C. elegans: How Neuropeptide Signaling Conveys Temporal Information
Peter Yates Si-Yi Chen 2013 The histone H2A deubiquitinase MYSM1 regulates CCR9 expression on CD4+ T cells and thymocytes
Lauren Geary Pradip Roy-Burman 2013 Role of cancer-associated fibroblast secreted annexin A1 in generation and maintenance of prostate cancer stem cells
Kevin Haworth Paula Cannon 2013 Molecular characterization of the HIV-1 Vpu protein and its role in antagonizing the cellular restriction factor Bst-2/tetherin both in vitro and in vivo
Ji-Young Lee James Ou 2013
Yvonne Leung Cheng Ming Chuong 2013 Characterization of new stem/progenitor cells in skin appendages
Jiahua Li Robert Farley/ Alan Yu 2013 Structural-functional study of the paracellular ion pore
Biquan Luo Amy Lee 2013 The role of endoplasmic reticulum chaperones in regulating hematopoietic stem cells and hematological malignancies
Mien Nguyen Alicia McDonough 2013 Integrated regulation of transporters along the nephron to maintain electrolyte and fluid homeostasis
Divya Sahu Wei Li 2013 Characterization of a fragment in secreted Hsp90alpha with potential therapeutic benefits in wound healing and cancer
Christopher Scannell Beth Lawlor 2013 The role of LGR5 in the pathogeneis of ewing sarcoma: A marker of aggressive disease and a contributor to the malignant phenotype
Sarah Utley Kasper Wang 2013 The role of fibroblast growth factor signaling on postnatal hepatic progenitor cell expansion
Ryan Walker Michael Goran 2013 Genetic and dietary determinants of nonalcoholic fatty liver disease in Hispanic children
Orquidea Garcia David Warburton 2013 Immunomodulatory and regenerative potential of amniotic fluid stem cells as a treatment strategy for pulmonary fibrosis
Chia-Ling Hsieh Jeannie Chen 2013 Protein phosphatase 2A and annexin A5: Modulators of cellular functions
Suhn Rhie Gerhard Coetzee 2013 Breast epithelial cell type specific enhancers and functional annotation of breast cancer risk loci
Aarti Rohira Debbie Johnson 2013 Sumoylation regulates RNA polymerase III – Dependent transcription via Maf1
Hui Shen Peter W. Larid 2013 Integrative genomic and epigenomic analysis of human cancer
Seyedmehdi Shojaee Peter W. Larid 2013 Induction of hypersignaling as a therapeutic approach for treatment of BCR-ABL1 positive Acute Lymphoblastic Leukemia (ALL) cells
Sheng-Fang Su Peter A. Jones 2013 Identification of novel epigenetic biomarkers and microRNAs for cancer therapeutics
Srividya Swaminathan Markus Mushen 2013 Loss of checkpoint controls in acute lymphoblastic leukemia
Shao Hung Tsen Wei Li 2013 The mechanism by which extracellular Hsp90alpha Promotes cell migration: Implications in wound healing and cancer progression
Tian Wang 2013 Mechanisms of retinal degeneration caused by genetic and environmental factors
Helty Adisetiyo Pradip Roy-Burman 2012 Exploration of the roles of cancer stem cells and survivin in the pathogenesis and progression of prostate cancer
Lauren Congdon Judd Rice 2012 Multiple functions of the PR-Set7 histone methyltransferase: From transcription to the cell cycle
Chendhore Veerappan Judd Rice 2012 Epigenetic plasticity of cultured female human embryonic stem cells and regulation of gene expression and chromatin by PR-SET7 mediated H4K20me1
Meng Xu Xiaojiang Chen 2012 Biochemical characterization and structural analysis of two hexameric helicases for eukaryotic DNA replication
Christine Cao Agnieszka Kobielak 2012 The role of alpha-catulin during tumor progression and early mouse development
Mohamed Hassanein Fredrick Schumacher 2012 Common genetic variation and obesity: A multi-ethnic and pediatric perspective
Kaijie He Amir Goldkorn 2012 The cancer stem-like phenotype: Therapeutics, phenotypic plasticity and mechanistic studies
Kuo-Chan Hung Richard Roberts 2012 Developing peptide and antibody-mimetic ligands for the cell surface receptor beta2AR and DC-SIGN
Reza Kalhor Lin Chen 2012 Exploring three-dimensional organization of the genome by mapping chromatin contacts and population modeling
Ben Lam Gregor Adams 2012 The calcium-sensing receptor in the specification of normal and malignant hematopoietic cell localization in the bone marrow microenvironment
Beth Palian Debbie Johnson 2012 Maf1 is a novel target of the tumor suppressor PTEN and a negative regulator of lipid metabolism
Anil Sindhurakar 2012 Development of interlimb stepping for locomotion in the chick: Impact of light exposure during embryogenesis
Zong Wei Wange Lu 2012 The molecular mechanisms of somatic cell reprogramming
Berenice Aguilar Young-Kwon Hong 2012 Kaposi’s Sarcoma associated Herpes-virus induces cellular PROX1 expression to modulate host gene expression that benefits viral infection and oncogenesis
Ankita Das Gage Crump 2012 Tissue interactions & molecular pathways in specification of the ectomesenchyme from cranial neural crest
Jennifer Mastroianni Andre Ouellette 2012 Paneth cell alpha-defensins in mouse enteric innate immunity
Jordan Pomeroy 2012 Derivation and characterization of human embryonic stem (hES) cells and human induced pluripotent stem (hiPS) cells in clinical grade conditions
Suhaida Selamat Ite Larid-Offringa 2012 DNA methylation changes in the development of lung adenocarcinoma
Kenneth Tai Andre Ouellette 2012 Bactericidal effects of natural and variant alpha-defensin peptides
Andrew Gray Martin Kast 2011 The effect of tumor-mediated immune suppression on prostate cancer immunotherapy
Arum Han Wei Li 2011 Molecular mechanism of transforming growth factor-beta signaling in skin wound healing
Irina Ianculescu Michael Stallcup 2011 One play, many actors: The many roles coregulators play in nuclear receptor mediated transcription
Hee Kim Jae U. Jung 2011 Beclin1-interacting autophagy protein Atg14L targets SNARE-associated protein Snapin to coordinate endocytic trafficking
Daniel Purcell Michael Stallcup 2011 Two faced coregulator: Coactivation and corepression of transcription by histone methyltransferase G9a
Narges Rashidi Gregor Adams 2011 Regional localization and regulation of hematopoietic stem cells in the bone marrow stem cell niche
Nimanthi Jayathilaka Dr. Lin Chen 2011 Inhibition of the interaction between class IIa histone deacetylases and myocyte enhancer factor 2 by small molecules
Vivian Medina Bangyan Stiles 2011 Pten deletion induced tumor initiating cells: Strategies to accelerate the disease progression of liver cancer
Kyle Nakamura Grace Aldrovandi 2011 Route-specific selection during mother-to-child transmission of HIV-1
Christopher Schafer Robert Maxson 2011 The temporal and tissue specific requirement of Msx genes in murine skull vault osteogenesis
Steven Tsai Carolyn Lutzko 2011 Investigating the role of OCT4 isoforms in human embryonic stem cell self-renewal and differentiation
Shiuan Wey Amy Lee 2011 The role of endoplasmic reticulum protein GRP78 in normal hematopoiesis and PTEN-null leukemogenesis
Jingjing Zhou Henry Sucov 2011 Endothelial neuropilin disruption in mice causes DiGeorge syndrome-like malformations independent of Tbx1
John Kaddis 2011 Influence of RNA labeling on expression profiling of microRNAs.
Hyunjung Kim Woojin An 2011 Targeting chromatin modification in human cancer: SMYD3 mediated ERalpha Transcription regulation. Cooperative role between H3.3 and HP1gamma
Melissa Lechner Alan Epstein 2011 Human myeloid-derived suppressor cells in cancer: Induction, functional characterization, and therapy
Houtan Noushmehr Peter Laird 2011 Integrated genomic & epigenomic analyses of glioblastoma multiforme: Methods development and application
Karoline Rostamiani Michael Baudry 2011 Brain-derived neurotrophic factor (BDNF)-dependent activation of calpain: Involvement of ERK pathway and regulation of AMPA receptor function and stability
Jacob Andrade 2010 Pre-transplant conditioning and the role of the microenvironment during hematopoietic reconstitution
Meleeneh Kazarian 2013 Anti-Hu immuno-responsiveness in small-cell lung cancer
Rahul Nahar Markus Mushen 2010 Pre-B cell receptor signaling in acute lymphoblastic leukemia
Maya Otto-Duessel John Wood 2010 Effects of vitamin D perturbation on cardiac iron overload
Shikhar Sharma Peter Jones 2010 Role of DNA methyltransferases 3A and 3B in inheritance of DNA methylation patterns
Miao Wang Amy Lee 2010 Role of endoplasmic reticulum chaperones GRP78 and GRP94 in regulating unfolded protein response and cell survival
Yu-Hao Chang 2010 Structural studies of two key factors for DNA replication in eukaryotic cells
Nancy Chen Michael Cody 2010 Developing and testing a heuristic-systematic model of health decision making: The role of affect, trust, confidence and media influence
Hao-Ru Hsu Elizabeth Lawlor 2010 Harnessing the power of stem cell self-renewal pathways in cancer: Dissecting the role of BMI-1 in Ewing’s sarcoma initiation and maintenance
Shun-Ping Huang Cheryl Craft 2010 Exploring alternative roles of visual arrestin 1 in photoreceptor synaptic regulation and deciphering the molecular pathway of retinal degeneration using mouse knockout technology
Melissa LaBonte Robert D. Landner 2010 Evaluating novel chemotherapeutic strategies in colorectal and gastric cancer: The role of histone deacetylase inhibitors and human epidermal receptor family inhibitors
Kiyoharu Miyagishima Alspakkam Sampath 2010 An investigation of dark adaptation: The role of metabolism and alternative rod pathways in shaping visual sensitivity following bright light
Adam Raff Martin Kast 2010 The silenced sentinel: A human papillomavirus type 16 immune evasion mechanism targeting Langerhans cells
Eric Schulze Qi-Ying Ying 2010 Investigating the role of STAT3 in mouse and rat embryonic stem cell self-renewal and differentiation
Stephanie Stanford Nunzio Bottini 2010 The molecular mechanism underlying the autoimmune-associated PTPN22 R620W variation and the quest for therapeutics
Guanhua Xie Laurie DeLeve 2010 Acceleration of resolution of cirrhosis by normalization of liver sinusoidal endothelial cell (LSEC) phenotype through the cGMP signaling pathway
Rosanne Yetemian Cheryl Graft 2010 Elements of photoreceptor homeostasis: Investigating phenotypic manifestations and susceptibility to photoreceptor degeneration in genetic knockout models for retinal disease
Fiona Hanner Janos Peti-Peterdi 2010 Connexins and pannexins in the kidney: A study of their expression, regulation, and function
Changhan Lee Valter Long 2010 Fasting-based differential stress resistance to enhance cancer treatment: A novel strategy to protect normal cells and sensitize cancer cells to chemotherapy
Minyoung Lim Pradip Roy-Burman 2010 The study of the role of bone morphogenetic proteins in prostate cancer progression
Chen-Yin Ou Michael Stallcup 2010 Differential role of two coactivators, CCAR1 and CARM1, for dysregulated beta-catenin activity in colorectal cancer cell growth and gene expression
Lan Qin Yuan Ping Han 2010 Histone deacetylase 4 represses matrix metalloproteinases in myofibroblastic hepatic stellate cells
Anne Riquier 2009 Regulation of renal proximal tubule sodium transporters during high blood pressure
Denise Carbonaro Donal B. Kohn 2009 Cell and gene therapy in the murine model of adenosine deaminase deficiency
Eszter Pais Donal B. Kohn 2009 Stem cell and gene transfer-based approaches to generate insulin-producing cells
Jung Kang 2008